Understanding Wave Propagation in the Arterial Tree

Monday, December 4, 2017 - 1:00pm
3110 Etcheverry Hall
Professor Nikos Stergiopulos

Laboratory of Hemodynamics and Cardiovascular Technology
Swiss Federal Institute of Technology


Recent advances in imaging modalities used frequently in clinical routine can provide description of the geometrical and hemodynamical properties of the arterial tree in great detail. The combination of such information with models of blood flow in the arterial tree can provide further information, such as details in pressure and flow waves or details in the local flow field. Such knowledge maybe be critical in understanding the development or state of arterial disease and can help clinicians perform better diagnosis or plan better treatments. In the present review, the state of the art of arterial tree models is presented, focusing on 1-D wave propagation models. Our development of a generic and patient-specific model of the human arterial tree permitting to study pressure and flow waves propagation in patients is presented. The predicted pressure and flow waveforms are in good agreement with the in vivo measurements. I will discuss the utility of these models in different clinical applications and potential future developments of clinical interest.


Nikos Stergiopulos received his M.S. in Mechanical Engineering from the National Technical University of Athens, Greece, in 1985 and his Ph.D. in Biomedical Engineering from Iowa State University, USA, in 1990. Nikos holds also a degree in Management of Technology from IMD. He is currently Full Professor and Director of the Laboratory of Hemodynamics and Cardiovascular Technology at the Swiss Federal Institute of Technology in Lausanne, Switzerland. His main research interests are Hemodynamics, Cardiovascular Mechanics and Medical Implant Technology. He has authored more than 180 peer review papers and holds more than 15 patents in medical technology. Nikos has founded four medical technology startups and is actively supporting technology transfer from the academic lab to the real world.


Hosted by: Associate Professor Shawn Shadden, 5126 Etcheverry Hall, 510- 664-9800, shadden@berkeley.edu