Molecular Cell Biomechanics Laboratory
208A Stanley Hall #1762
University of California at Berkeley
Berkeley, CA 94720-1762
|1991||B.A.Sc., Sharif University of Technology|
|1994||M.A.Sc., University of Waterloo|
|1999||Ph.D., University of Toronto|
|1999-2000||Post-Doc, Computer Science Department, University of Toronto|
|2000-2002||Post-Doc, MIT and Harvard Medical School/Mass. General Hospital|
|2002-2003||Research Scientist, Biological and Mechanical Engineering, MIT|
|2003-2004||Principal Research Scientist, Biological and Mechanical Engineering, MIT|
|2005-2010||Assistant Professor, Department of Bioengineering, University of California, Berkeley|
|2010-2013||Associate Professor, Department of Bioengineering, University of California, Berkeley|
|2011||Visiting Professor, Department of Bioengineering, EPFL, Lausanne, Switzerland|
|2012-2013||Associate Professor, Department of Mechanical Engineering, University of California, Berkeley|
|2012-present||Faculty Engineer, Division of Physical Biosciences, Lawrence Berkeley National Lab|
|2013-present||Professor, Departments of Bioengineering and Mechanical Engineering, University of California, Berkeley|
|2012-2014||Faculty Director, UC Berkeley Master of Bioengineering Program|
|2014-2015||Faculty Co-Director, Berkeley-UCSF Master of Translational Medicine Program|
Multiscale Biomechanics of Cardiovascular Disease and Brain Injury; Molecular and Cellular Mechanobiology; Mechanics of Integrin-Mediated Focal Adhesions; Mechanics of the Nuclear Pore and Nucleocytoplasmic Transport
To learn more about Professor Mofrad's research, please visit the Molecular Cell Biomechanics Laboratory website.
BioE C215 / ME C216: Mechanobiology of the Cell: Dynamics of the Cytoskeleton and Nucleus
This (graduate) course brings together various viewpoints and modeling and measurement approaches in the study of cytoskeletal and nuclear mechanics and dynamics. This course is intended for graduate students in Bioengineering and Mechanical Engineering with prior exposure to continuum mechanics. No prior knowledge in Biology is assumed.
ME 211: The Cell as a Machine
This course offers a modular and systems mechanobiology (or “machine”) perspective of the cell. Two vitally important components of the cell machinery will be studied in depth: (1) the integrin-mediated focal adhesions system that enables the cell to adhere to, and communicate mechano-chemical signals with, the extracellular environment, and (2) the nuclear pore complex, a multi-protein gateway for traffic in and out of the nucleus that regulates gene expression and affects protein synthesis. This course is intended for graduate students in Mechanical Engineering. No prior knowledge in Biology is assumed.
BioE102: Biomechanics: Analysis and Design
This (junior level undergraduate) course develops and applies the methods of continuum mechanics to biomechanical phenomena over a range of length scales, from cell to tissue and organ levels. It is intended for junior undergraduate students in Bioengineering who have been exposed to undergraduate physics, linear algebra and differential equations. The course will equip the students with a deep understanding of principles of biomechanics. The intuitions gained in this course will guide the design of biomedical devices and help the understanding of biological/medical phenomena in health and disease.
BioE104: Biological Transport Phenomena
This course develops and applies scaling laws and the methods of continuum mechanics to biological transport phenomena over a range of length and time scales. It is intended for undergraduate students who have taken a course in differential equations, and an introductory course in physics. Preliminary understanding of biology and physiology is useful but not assumed. Example application areas include biomolecular transport in biological tissues, living organs, and in biomedical microdevices.
ME 120: Computational Biomechanics Across Multiple Scales
This computational lab course applies the methods of computational modeling and continuum mechanics to biomedical phenomena spanning various length scales ranging from molecular to cellular to tissue and organ levels. It is intended for senior undergraduate students in Mechanical Engineering who have been exposed to undergraduate continuum mechanics (statics and strength of materials).
BioE C112 / ME C115: Molecular Cell Biomechanics
This (senior level undergraduate) course develops and applies scaling laws and the methods of continuum and statistical mechanics to biomechanical phenomena over a range of length scales, from molecular to cellular levels. This course is intended for senior undergraduate students in Bioengineering and Mechanical Engineering with prior exposure to continuum mechanics (BioE102 or ME C85). No prior knowledge in Biology is assumed.