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Title:
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Models and Methods in Computational Vascular and Cardiovascular Mechanics

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Organizers:
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Y. Bazilevs (Email: bazily@ices.utexas.edu)
ICES, UT Austin
201 E. 24th Street
Austin, Texas 78712

V.M. Calo (Email: victor@ices.utexas.edu)
ICES, UT Austin
201 E. 24th Street
Austin, Texas 78712

C.A. Taylor (Email: taylorca@stanford.edu)
Stanford University
James H. Clark Center, Room E350B
318 Campus Drive
Stanford, CA 94305-5431

T.J.R. Hughes (Email: hughes@ices.utexas.edu)
ICES, UT Austin
201 E. 24th Street
Austin, Texas 78712

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Minisymposium description:
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Over the past decade there has been significant progress in the development of
models and computational methods for blood flow simulation. The
state-of-the-art in vascular and cardiovascular simulation involves coupled
fluid and structural analyses employing three-dimensional, patient-specific
modeling of arterial geometries. Although the level of sophistication of the
current methodologies is high, several outstanding issues need to be addressed
in a systematic way in order to obtain medically realistic simulations and make
simulation-based approaches truly predictive. In this minisymposium we hope to
have a collection of talks that address, but are not limited to the following
topics:

- Specification of physiologically realistic boundary conditions that
  incorporate the effect of surrounding organs and smaller vessels
- Detailed description of material properties of biological tissue, including
  anisotropy, layers, growth and remodeling
- Various computational methodologies for coupled fluid-structural simulation
  that include ALE and space-time finite element and isogeometric analysis
  approaches, immersed boundary and finite element techniques, etc.
- Aspects of patient-specific geometry modeling and building of
  analysis-suitable vascular and cardiovascular geometries
- Applications of the above procedures to various patient-specific models of
  arterial systems and the heart
- Modeling and computation of the venous side of the circulation
- Importance of non-Newtonian and reological effects in modeling blood as an
  incompressible Navier-Stokes fluid.
- The dynamics of fluidic transport in vessels and conduits in nano-scale
  channels employing methodologies of analysis and modeling that bridge the
  continuum with stochastic mechanics and molecular dynamics.
- Dynamics of nanoparticle transport in blood vessels, in particular with
  respect to pathological endothelium.
- Modeling of the distribution of pharmaceutical agents, and their effects on
  the growth of malignant disease.