June 1997 Cryosurgical Publications

	June 3d	June 10th	June 17th	June 24th
BIOSYS
MEDLINE

June 3d, 1997

1. Johnson, L B; Krebs, T; Wong-You-Cheong, J; Njoku, M; Plotkin, J S; Daly, B;
   Wilson, S; Kuo, P C.
     Cryosurgical debulking of unresectable liver metastases for palliation of
   carcinoid syndrome.
     Surgery (St Louis), v.121, n.4, (1997): 468-470.

  

June 3d, 1997

June 10th, 1997

1. Connolly, J A; Shinohara, K; Presti, J C Jr; Carroll, P R.
     Prostate-specific antigen after cryosurgical ablation of the prostate:
   Defining the appropriate response.
     Urologic Clinics of North America, v.24, n.2, (1997): 415-420.

  

June 10th, 1997

1. Kluppel M; Reinhard T; Sundmacher R; Daicker B.
     [Therapy of advanced amoeba keratitis with keratoplasty a chaud and
     adjuvant cryotherapy].
   Ophthalmologe, 1997 Feb, 94(2):99-103.
     Language:  German.
       (UI:  97235746)

Abstract: BACKGROUND: Since the mid-1980s acanthamoeba keratitis has been
    diagnosed with increasing frequency, especially in contact lens wearers.
    The assignment to specialized centers is often delayed many months and
    there is hardly any chance of controlling the disease by conservative
    treatment alone. In these cases, penetrating keratoplasty offers the only
    chance for rehabilitation. The therapeutic role of penetrating keratoplasty
    and supportive intraoperative cryotherapy is demonstrated by the courses of
    six patients with unilateral acanthamoeba keratitis. PATIENTS AND METHODS:
    The data of six patients aged 41.2 (22-63) years with medically
    uncontrollable acanthamoeba keratitis were evaluated retrospectively. The
    diagnosis was confirmed histologically in all cases. All patients were
    contact lens wearers. They underwent a total of ten keratoplasties between
    November 1986 and January 1995. The donors were 44.8 (23-58) years of age.
    The transplant diameters varied between 7.7 and 9.5 mm. The margins of the
    host cornea were intraoperatively frozen by a cryoprobe in three patients
    with a far advanced stage of corneolimbal parasitic infiltration. RESULTS:
    During a follow-up period of +/-10.2 (1-22) months, five of six eyes were
    rehabilitated with visual acuities between 0.4 and 1.0. One eye went blind
    after the fourth keratoplasty because of uncontrollable secondary glaucoma.
    After three keratoplasties with simultaneous application of cryocoagulation
    because of an especially high risk of persisting acanthamoeba infection,
    all corneae remained clear and free of recurrences. CONCLUSIONS: In
    advanced acanthamoeba keratitis which has not responded to conservative
    treatment, penetrating keratoplasty not only provides elimination of the
    pathogen, but also good functional results. In far advanced stages, the
    intraoperative application of cryocoagulation for parasite elimination in
    the host cornea seems to be a very effective measure against local
    recurrences of the infection.

June 17th, 1997

1. Long, J P; Fallick, M L; Rand, W.
     Increased serum total creatine kinase and creatine kinase isoenzyme MB
   after cryosurgical ablation of the prostate.
     Journal of Urology, v.157, n.5, (1997): 1723-1726.

Abstract:
     Purpose: Several reports have documented that the MB isoenzyme of creatine
     kinase is present in prostatic tissue. However, since it has been shown
     that lower urinary tract manipulations, including transurethral
     prostatectomy, do not significantly increase serum creatine kinase
     isoenzyme MB levels, such elevations, which are found in patients after
     prostatic surgery, are believed to be specific for myocardial infarction.
     We examined whether cryosurgical ablation of the prostate altered serum
     creatine kinase or isoenzyme MB levels. Materials and Methods: In 81
     consecutive patients undergoing routine cryosurgical ablation of the
     prostate serum levels of creatine kinase and creatine kinase isoenzyme MB
     were measured from peripheral blood specimens drawn preoperatively, in the
     recovery room and at 8 and 24 hours postoperatively. Postoperative
     electrocardiograms were compared to the preoperative study. Results: In 72
     of 81 patients (89%) significant elevations in creatine kinase and
     creatine kinase isoenzyme MB levels were noted at all time points after
     cryosurgical ablation of the prostate and appeared to reach a peak at 16
     hours postoperatively. The mean increases within the first 8 hours after
     cryosurgical ablation of the prostate were 1,355 units per 1. for creatine
     kinase and 46.6 ng./ml. for creatine kinase isoenzyme MB. No patient had
     any significant changes on the postoperative electrocardiogram. All 9
     patients (11%) who did not have significant creatine kinase or creatine
     kinase isoenzyme MB levels after cryosurgery had undergone prior
     cryosurgery or combined radiation and hormonal therapy. Conclusions:
     Cryosurgical ablation of the prostate appears to produce elevations in
     serum creatine kinase and creatine kinase isoenzyme MB, which are specific
     to the procedure. Assays for creatine kinase isoenzyme MB are unreliable
     to render a diagnosis of myocardial infarction after cryosurgical ablation
     of the prostate.
  

June 17th, 1997

1. Lindgren G; Larko O.
     Long-term follow-up of cryosurgery of basal cell carcinoma of the eyelid.
   Journal of the American Academy of Dermatology, 1997 May, 36(5 Pt 1):742-6.
       (UI:  97291997)

Abstract: BACKGROUND: Basal cell carcinoma (BCC) is the most common malignant
    tumor of the eyelid and its incidence is increasing. It remains to be
    established which is the best treatment in terms of safety and
    cost-effectiveness. OBJECTIVE: Our purpose was to analyze the long-term
    treatment results and possible side effects of cryosurgery of eye

June 24th, 1997

June 24th, 1997